Somatostatin

A 14-amino acid peptide named for its ability to inhibit pituitary GROWTH HORMONE release, also called somatotropin release-inhibiting factor. It is expressed in the central and peripheral nervous systems, the gut, and other organs. SRIF can also inhibit the release of THYROID-STIMULATING HORMONE; PROLACTIN; INSULIN; and GLUCAGON besides acting as a neurotransmitter and neuromodulator. In a number of species including humans, there is an additional form of somatostatin, SRIF-28 with a 14-amino acid extension at the N-terminal.

Also Known As:

Somatotropin Release-Inhibiting Factor; Somatotropin Release Inhibiting Hormone; SRIH-14; Somatofalk; Somatostatin, Cyclic; Stilamin; Somatostatin 14; Somatotropin Release Inhibiting Factor; Cyclic Somatostatin; Somatostatin-14; Somatotropin Release-Inhibiting Hormone

Pharmalogical Action Categories:

Hormones

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 82104
  - Peptide Hormones: 1361
    - Pancreatic Hormones: 116
      - Somatostatin: 9042
    - Hypothalamic Hormones: 69
      - Pituitary Hormone Release Inhibiting Hormones
        Somatostatin: 9042
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Nerve Tissue Proteins: 3
    - Neuropeptides: 6903
      - Hypothalamic Hormones: 69
        Pituitary Hormone Release Inhibiting Hormones
        Somatostatin: 9042
- Peptides: 84029
  - Neuropeptides: 6903
    - Hypothalamic Hormones: 69
      - Pituitary Hormone Release Inhibiting Hormones
        Somatostatin: 9042
  - Peptide Hormones: 1361
    - Pancreatic Hormones: 116
      - Somatostatin: 9042
    - Hypothalamic Hormones: 69
      - Pituitary Hormone Release Inhibiting Hormones
        Somatostatin: 9042

B C Carlyle Selected Research

B C Carlyle Research Topics

Disease

Drug/Important Bio-Agent (IBA)